Oklahoma Sooners vs South Carolina NCAAF Betting Prediction
PublishedOctober 14, 2025,            Posted By: Maria Uebelhor
Last updated:October 14, 2025 ,

NCAAF Oklahoma Sooners vs South Carolina Prediction 10/18

The Oklahoma Sooners will take on the South Carolina Gamecocks on Saturday, October 18, 2025. The game will be held at Williams-Brice Stadium in Columbia, SC, with a start time of 12:45 PM ET. Fans can watch the game on SECN. This is Week 8 of the 2025 regular season. The Sooners have a 5-1 record, while the Gamecocks stand at 3-3.

Oklahoma vs. South Carolina Betting Prediction

  • Money Line Prediction: Oklahoma Sooners -211. Oklahoma has a strong record as a favorite, winning 12 of their last 13 games in this role. They are also ranked #14 in the AP poll, showing their strength this season.
  • Over/Under Prediction: Under 43.5. Both teams have shown solid defensive capabilities, with Oklahoma allowing only 59 points this season. South Carolina’s recent games have also tended to stay under this total.

Team Trends

  • Oklahoma Sooners are ranked #14 in the AP Poll and #13 in the Coaches Poll.
  • South Carolina Gamecocks have a home record of 2-1 this season.
  • Oklahoma Sooners have a road record of 1-1 this season.
  • The game will be played at Williams-Brice Stadium in Columbia, SC.
  • Oklahoma’s defense ranks 3rd in sacks with 23 this season.

Oklahoma vs South Carolina Preview

The Oklahoma Sooners are set to visit the South Carolina Gamecocks in Week 8 of the 2025 season. The Sooners hold a strong 5-1 record, placing them high in the rankings at #14 in the AP Poll and #13 in the Coaches Poll. They are coming off a close loss, and their road performance stands at 1-1. The Sooners aim to improve their conference record, which currently sits at 1-1.

The Gamecocks have a balanced 3-3 record and are looking to bounce back after their recent loss. They have been solid at home with a 2-1 record. South Carolina’s conference record is 1-3, and they are eager to climb up the standings. This game at Williams-Brice Stadium is an opportunity for both teams to make a statement in the Southeastern Conference.

Gamecocks’ Home Turf Advantage

The South Carolina Gamecocks play in the Southeastern Conference. They call Williams-Brice Stadium their home. This season, they have a home record of 2-1.

LaNorris Sellers leads the team as the top quarterback. He has played in 6 games with 1,010 passing yards. Sellers also has 4 passing touchdowns and 2 interceptions.

Rahsul Faison is a key player at running back with 231 rushing yards over 6 games. He has scored 3 rushing touchdowns. Vandrevius Jacobs shines as a top wide receiver with 341 receiving yards in 5 games.

Sooners Ready for Battle

The Oklahoma Sooners are ranked 14th in the AP Poll and 13th in the Coaches Poll. They play in the Southeastern Conference, like the Gamecocks. This season, the Sooners have a record of 5-1.

John Mateer is the leading quarterback for the Sooners. He has passed for 1,417 yards in 5 games. Mateer has thrown 6 touchdowns and 6 interceptions.

In the running back position, Tory Blaylock has rushed for 292 yards over 6 games. Blaylock has also scored 3 rushing touchdowns. Wide receiver Isaiah Sategna III stands out with 420 receiving yards and 3 touchdowns in 6 games.

Final Betting Pick

The Oklahoma Sooners are a strong pick for the money line at -211. They have won 12 of their last 13 games as favorites. Their solid record and #14 AP ranking show their strength this season. The Sooners have a 5-1 record, with their only loss coming against Texas. Their defense has been impressive, allowing only 59 points this season.

For the over/under, picking under 43.5 points looks good. Both teams have shown solid defense. Oklahoma has allowed only 59 points, while South Carolina has allowed 114 points this season. Recent games for South Carolina have stayed under this total. Oklahoma’s defense is ranked 23rd in points against, making a low-scoring game likely.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.