The South Carolina Gamecocks will travel to face the Ole Miss Rebels on Saturday, November 1, 2025. This Week 10 game will take place at Vaught-Hemingway Stadium in Oxford, MS. Kickoff is set for 7:00 PM ET, and the game will be broadcast on ESPN.

South Carolina vs. Ole Miss Betting Prediction

• Money Line Prediction: Ole Miss -498. Ole Miss has a strong home record, winning all five home games this season. South Carolina struggles on the road with a 1-2 record.
• Over/Under Prediction: Over 54.5. Ole Miss has a high-scoring offense, ranked 14th in points for, and South Carolina’s defense ranks 81st in points against.

Team Trends

• Ole Miss has a perfect home record this season, standing at 5-0.
• South Carolina has struggled in conference games, with a record of 1-5.
• Ole Miss ranks 5th in passing yards this season with 2,444 yards.
• South Carolina’s defense ranks 7th in interceptions with 6 this season.
• The game will take place at Vaught-Hemingway Stadium, an outdoor field in Oxford, MS.

South Carolina vs Ole Miss Preview

The South Carolina Gamecocks will visit the Ole Miss Rebels for a Week 10 game on Saturday, November 1, 2025. The Gamecocks hold a 3-5 record this season, struggling in the Southeastern Conference with a 1-5 record. They aim to break their three-game losing streak at Vaught-Hemingway Stadium.

On the other side, the Ole Miss Rebels have a strong 7-1 record and are ranked seventh in the AP poll. They remain unbeaten at home with a 5-0 record. The Rebels hope to continue their success and extend their one-game winning streak. The game will start at 7:00 PM ET and will be shown on ESPN.

Ole Miss Rebels: Team Overview and Season Performance

The Ole Miss Rebels are having a strong season with a 7-1 record. They are ranked #7 in the AP poll and #8 in the Coaches Poll. Ole Miss plays in the Southeastern Conference and calls Vaught-Hemingway Stadium home.

Trinidad Chambliss leads the Rebels as quarterback with 1,864 passing yards and nine touchdowns in eight games. Austin Simmons backs him up with 580 yards and four touchdowns in five games. On the ground, Kewan Lacy is the top running back with 696 rushing yards and 12 touchdowns.

The Rebels’ offense ranks 5th in passing yards with 2,444 and 37th in rushing yards with 1,457. Their defense has allowed 184 points, ranking 89th, with 13 sacks and three interceptions. Ole Miss is strong at home with a 5-0 record and recently won 34-26 against Oklahoma.

South Carolina Gamecocks: Season Journey and Key Players

The South Carolina Gamecocks have a 3-5 record this season. They play in the Southeastern Conference and call Williams-Brice Stadium home. Recently, they experienced a 22-29 defeat against Alabama.

LaNorris Sellers is the Gamecocks’ main quarterback. He has thrown for 1,356 yards and six touchdowns in eight games. Cutter Woods also played one game, throwing for 46 yards and one interception.

On the ground, Rahsul Faison leads with 298 rushing yards and three touchdowns over eight games. Nyck Harbor is a top wide receiver with 332 receiving yards and three touchdowns. The Gamecocks’ defense has given up 169 points and recorded 18 sacks and six interceptions this season.

Final Betting Pick

Ole Miss is a solid pick on the money line at -498. They have been strong at home with a perfect 5-0 record this season. Their offense ranks 14th in points scored, making them tough to beat at Vaught-Hemingway Stadium. South Carolina, on the other hand, has struggled on the road with a 1-2 record. This makes Ole Miss a reliable choice for a win.

The over 54.5 is also a good choice for this game. Ole Miss has a high-scoring offense, and South Carolina’s defense ranks 81st in points allowed. This combination suggests a high-scoring game. Ole Miss’s recent games have shown they can put up points, and South Carolina’s defense might have trouble keeping up. This makes the over a reasonable bet.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.