On Sunday, October 19, 2025, the Atlanta Falcons will visit the San Francisco 49ers at Levi’s Stadium in Santa Clara, CA. The game starts at 8:20 PM and will be shown on NBC. The Falcons have a 3-2 record, while the 49ers stand at 4-2 this season.

Falcons vs. 49ers Betting Prediction

• Money Line Prediction: San Francisco 49ers -134. The 49ers have a strong home record and have shown good performance in past games at Levi’s Stadium. Their offense, led by Brock Purdy and Christian McCaffrey, can be effective against the Falcons’ defense.
• Over/Under Prediction: Under 47.5 (-114). Both teams have shown solid defensive capabilities, and recent games have not been high-scoring. This suggests the total might stay under the set line.

Team Trends

• The Atlanta Falcons have a road record of 1-1-0 this season.
• The San Francisco 49ers have a home record of 1-1-0 this season.
• Atlanta Falcons’ head coach is Raheem Morris.
• The San Francisco 49ers are part of the NFC West division.
• The game will be played at Levi’s Stadium in Santa Clara, CA.

Falcons vs 49ers Preview

The Atlanta Falcons are heading to Levi’s Stadium with a 3-2 record. They are second in the NFC South, trailing the Buccaneers. Michael Penix Jr. is expected to throw for over 220 yards. Bijan Robinson looks to add to his rushing yards with a strong performance.

The San Francisco 49ers stand at 4-2, leading the NFC West. Brock Purdy is projected to pass for more than 228 yards. Christian McCaffrey aims to contribute with both rushing and receiving yards. The 49ers will try to bounce back from their last loss and maintain their division lead.

San Francisco 49ers: A Look at the Home Team

The San Francisco 49ers have a strong record this season, sitting at 4-2. At Levi’s Stadium, their home record stands at 1-1. Head coach Kyle Shanahan leads the team, guiding them to a successful division record of 3-0.

Quarterback Brock Purdy is projected to throw for 228.3 yards with 1.6 touchdowns in the upcoming game. Running back Christian McCaffrey is a key player with 70.4 rushing yards and 5.6 receptions projected. Wide receiver Kendrick Bourne is another notable player, expected to gain 53.4 receiving yards.

The 49ers have faced challenges with injuries, including key players like George Kittle and Nick Bosa on the injured reserve. Despite these setbacks, the team continues to perform well. Their offensive stats from last season ranked 4th in passing yards, showcasing the strength of their passing game.

Atlanta Falcons: Road Warriors Ready for Battle

The Atlanta Falcons are led by head coach Raheem Morris. Their record this season is 3-2. On the road, they have won one game and lost one game.

Quarterback Michael Penix Jr. is expected to pass for 223.6 yards with 1.3 touchdowns. Running back Bijan Robinson is projected to rush for 85.6 yards and catch 3.7 passes. Wide receiver Drake London might gain 72.0 receiving yards.

The Falcons’ defense ranked 22nd last season in opponent scores. They recorded 31 sacks and recovered 6 fumbles. Injuries include key players like Jake Matthews and Darnell Mooney, who are listed as questionable.

Final Betting Pick

The San Francisco 49ers are favored with a money line of -134. They have a strong performance at home, making them a solid pick. Brock Purdy and Christian McCaffrey are key players in their offense. They can challenge the Falcons’ defense effectively.

The over/under is set at 47.5, and choosing under is a good option. Both teams have shown solid defense in recent games. The Falcons have allowed low scores in several games, and the 49ers have a strong defensive record at home, which supports this pick.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.