The Cincinnati Bengals will travel to face the Buffalo Bills on Sunday, December 7, 2025. The game will take place at Highmark Stadium in Orchard Park, NY. Kickoff is scheduled for 1:00 PM and will be broadcast on FOX. The Bengals have a 4-8 record, while the Bills stand at 8-4 this season.

Bengals vs. Bills Betting Prediction

• Money Line Prediction: Buffalo Bills -265. The Bills have a strong home record at 5-1 this season. They also won their last home game against the Tampa Bay Buccaneers, scoring 44 points.
• Over/Under Prediction: Under 52.5. The Bills’ defense ranks 11th in opponent scoring, and the Bengals have struggled offensively in recent games, scoring only 12 points against the Steelers.

Team Trends

• The Buffalo Bills have a strong home record this season, with 5 wins and 1 loss.
• Cincinnati Bengals recently won an away game against the Baltimore Ravens with a score of 32-14.
• Joe Burrow of the Bengals had 261 passing yards and 2 touchdowns in their last game against the Ravens.
• Buffalo Bills defeated the Pittsburgh Steelers 26-7 in their most recent away game.
• Josh Allen of the Bills had 123 passing yards and 1 touchdown in their last game against the Steelers.

Bengals vs Bills Preview

The Cincinnati Bengals are set to play against the Buffalo Bills on December 7, 2025. The Bengals have struggled this season with a 4-8 record, placing them third in the AFC North. They hope to build on their recent win as they face a tough Bills team. Joe Burrow will lead the Bengals’ offense, aiming to connect with key receivers like Ja’Marr Chase and Tee Higgins. Chase is projected to gain 82.6 receiving yards, which could be crucial for the Bengals’ chances.

The Buffalo Bills, with an 8-4 record, are second in the AFC East. They come into this game with a one-game winning streak. Josh Allen is expected to be a major factor, with projections of 248 passing yards and 2.1 touchdowns. The Bills’ defense will aim to contain the Bengals’ offensive threats. Playing at home, the Bills have been strong, winning five out of six games at Highmark Stadium this season. This matchup could impact playoff standings as the Bills look to secure their spot.

Buffalo Bills: Home Team Insights

Josh Allen is the top quarterback for the Buffalo Bills. This season, Allen has 2,832 passing yards and 19 touchdowns. He ranks first in fantasy points among quarterbacks.

James Cook is the leading running back for the team. He has rushed for 1,228 yards and scored eight touchdowns. Cook also has 27 receptions for 236 yards.

Sean McDermott is the head coach of the Bills. The team plays their home games at Highmark Stadium. This season, the Bills have a record of 8-4-0 and are 5-1-0 at home.

Cincinnati Bengals: Road Warriors

Joe Burrow leads the Bengals as the top quarterback. He is projected to throw for 235.2 yards and score 1.9 touchdowns in this game. Burrow has not thrown any interceptions this season.

Chase Brown is the key running back for the Bengals. He has accumulated 704 rushing yards and scored two touchdowns over 12 games. Brown also contributed with 48 receptions, gaining 287 receiving yards.

Zac Taylor is the head coach of the Bengals. The team holds a 4-8 record this season, with a road record of 2-4. They play in the AFC North and their home games at Paycor Stadium.

Final Betting Pick

The Buffalo Bills are a solid pick for the money line at -265. They have a strong home record, winning 5 out of 6 games. Their recent performance at home against the Tampa Bay Buccaneers, where they scored 44 points, shows their offensive capability.

Choosing the under 52.5 for the total points is a good choice. The Bills’ defense ranks 11th in opponent scoring, which could limit the Bengals’ chances. The Bengals have struggled offensively, scoring only 12 points against the Steelers in a recent game.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.