The Las Vegas Raiders will play against the Indianapolis Colts on Sunday, October 5, 2025. The game will be held at Lucas Oil Stadium in Indianapolis. It will start at 1:00 PM and will be broadcast on FOX.

Raiders vs. Colts Betting Prediction

• Money Line Prediction: Colts -314. The Colts have a strong 2-0 home record this season, making them a solid choice against the Raiders, who have struggled with a 1-3 record overall.
• Over/Under Prediction: Over 48.0. Both teams have shown the ability to score, with the Colts averaging 377 points last season and the Raiders having high-scoring games recently.

Team Trends

• The Indianapolis Colts have a perfect home record this season, standing at 2-0.
• Las Vegas Raiders have a balanced away record of 1-1 this season.
• The Colts’ head coach is Shane Steichen, while the Raiders are led by Pete Carroll.
• In their last home game, the Colts won against the Denver Broncos with a score of 29-28.
• The Raiders’ only win this season was an away game against the New England Patriots, with a score of 20-13.

Raiders vs Colts Preview

The Las Vegas Raiders head to Lucas Oil Stadium to take on the Indianapolis Colts in Week 5 of the 2025 NFL season. The Raiders come into this game with a 1-3 record, looking to break a three-game losing streak. Quarterback Geno Smith is expected to lead the Raiders with a projected 252.8 passing yards and 1.5 touchdowns. Running back Ashton Jeanty will also play a key role, with projections of 65.6 rushing yards and 0.5 touchdowns.

The Colts have a 3-1 record and are at the top of the AFC South Division. They aim to bounce back after a loss in their last game. Daniel Jones is the quarterback for the Colts, projected to throw for 224.6 yards and 1.4 touchdowns. Running back Jonathan Taylor is another player to watch, with 92.7 rushing yards and 0.7 touchdowns predicted. The game will be broadcast on FOX at 1:00 PM, and the retractable roof of Lucas Oil Stadium will ensure weather conditions do not affect the play.

Colts Aim to Maintain Strong Home Performance

The Indianapolis Colts have a strong start with a 3-1 record. They have shown strength at Lucas Oil Stadium, going 2-0 at home. Head coach Shane Steichen is guiding the team in the AFC South division.

Quarterback Daniel Jones leads the team with solid passing stats. He has 1,078 passing yards and four touchdowns this season. Running back Jonathan Taylor is also a key player with 414 rushing yards and three touchdowns.

Wide receiver Michael Pittman Jr. is an important target with 234 receiving yards and three touchdowns. The team’s defense ranks high in interceptions, sitting at fourth with 16. The Colts aim to keep their momentum, despite some injuries affecting their roster.

Raiders Look to Improve on the Road

The Las Vegas Raiders have a 1-3 record this season. They have won one out of two games on the road. Head coach Pete Carroll leads the team in the AFC West division.

Quarterback Geno Smith is expected to play a key role with 252.8 passing yards and 1.5 touchdowns projected for this game. Running back Ashton Jeanty is another important player, with a projection of 65.6 rushing yards. Wide receiver Jakobi Meyers could contribute with 65.0 receiving yards.

The Raiders’ defense ranks 10th in opponent passing interceptions with 10. Injuries are a concern, with key players like Kolton Miller and Lonnie Johnson Jr. out. Michael Mayer and Eric Stokes are questionable for Week 5.

Final Betting Pick

The Colts are a strong pick for the money line at -314. They have a perfect 2-0 home record this season. Playing at Lucas Oil Stadium gives them an edge, especially against the Raiders who have a 1-3 record overall. The Colts’ balanced offense, with Daniel Jones at quarterback and Jonathan Taylor in the backfield, adds to their advantage.

For the over/under prediction, going over 48.0 points seems likely. Both teams have shown they can score. The Colts averaged 377 points last season, and the Raiders have had high-scoring games recently. With players like Geno Smith and Jakobi Meyers on the Raiders’ side, expect a game with plenty of points.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.