The Detroit Red Wings will visit the Buffalo Sabres at KeyBank Center on Wednesday, October 22, 2025, at 7:30 PM. The Red Wings have a strong start to the season with a 5-1-0 record. Meanwhile, the Sabres are looking to improve their 2-4-0 record. The game will be broadcast on TNT.

Red Wings vs. Sabres Betting Prediction

• Money Line Prediction: Detroit Red Wings -106. The Red Wings have a strong start with a 5-1 record. They have been performing well on the road, winning their last away game against the Toronto Maple Leafs.
• Over/Under Prediction: Over 6.0 (-116). Both teams have shown they can score, with the Sabres putting up 8 goals against Ottawa recently. The Red Wings have also scored 4 or more goals in several of their games.

Team Trends

• The Detroit Red Wings have a strong start to the season with a 5-1 record.
• Buffalo Sabres hold a 2-4 record and are ranked 15th in their conference.
• Detroit Red Wings are currently ranked 1st in their division.
• Buffalo Sabres recently secured a win against the Florida Panthers with a 3-0 score at home.
• Detroit Red Wings recently defeated the Edmonton Oilers with a 4-2 score at home.

Red Wings vs Sabres Preview

The Detroit Red Wings are gearing up for their game against the Buffalo Sabres. The Red Wings have been doing well with a 5-1-0 record. They hope to keep their momentum going at KeyBank Center.

On the other hand, the Buffalo Sabres are looking to turn things around. They have a 2-4-0 record and want to improve. The game will be shown on TNT, and fans are eager to see how it unfolds.

Buffalo Sabres: A Closer Look at the Home Team

The Buffalo Sabres have some key players to watch. Zach Benson, a left winger, has played 3 games and has 6 assists. Rasmus Dahlin, a defenseman, has also been active with 5 assists in 6 games. Josh Doan has been a solid right winger for the Sabres. He has scored 2 goals and made 3 assists in 6 games. Alex Tuch and Jason Zucker have also contributed with goals and assists. In the goalie department, Alex Lyon has played in all 6 games. He has made 183 saves but allowed 15 goals. The Sabres will rely on him to keep up his performance in the net.

Detroit Red Wings: Key Players and Game Insights

Dylan Larkin is a standout player for the Detroit Red Wings. He has played 6 games and scored 5 goals. Larkin also has 6 assists, making him a key player on the ice. Alex DeBrincat is another important player. He has participated in 6 games and contributed 6 assists. Although he hasn’t scored any goals yet, his assists show his playmaking ability. Cam Talbot is the main goalie for the Red Wings. He has played in 4 games and won 3 of them. Talbot has made 82 saves and allowed 6 goals, showing his skill in the net.

Final Betting Pick

The Detroit Red Wings have been strong this season with a 5-1 record. They have shown they can win on the road, as seen in their recent victory against the Toronto Maple Leafs. This makes the money line prediction of Detroit Red Wings -106 a good pick, even as the underdog. Their solid conference and division records also add confidence to this pick.

The over/under prediction of over 6.0 (-116) is supported by both teams’ recent performances. The Buffalo Sabres scored 8 goals against the Ottawa Senators, showing they can put points on the board. The Red Wings have consistently scored 4 or more goals in several games, indicating a high-scoring potential for this game. With both teams capable of scoring, the over seems likely.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.